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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV) (Video) | JoVE

DOI :

10.3791/2078-v

September 14th, 2010

September 14th, 2010

12,390 Views

1Department of Microbiology & Immunology and the Center for AIDS Health Disparities Research, Meharry Medical College

Host cell factors play a critical role in the establishment and maintenance of Kaposi's sarcoma (KS). We outline methods to identify host cell factors altered in KSHV-infected DMVEC cells, and in KS tumor tissue. Cellular genes altered by virus will serve as potential target(s) for novel therapeutics.

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