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Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

DOI :

10.3791/224-v

July 4th, 2007

July 4th, 2007

17,684 Views

1Department of Physiology and Biophysics, University of California, Irvine (UCI)

This video demonstrates the induction and clinical scoring of an animal model of multiple sclerosis: chronic-relapsing experimental autoimmune encephalomyelitis in DA rats. The disease, induced by immunizing rats with an emulsion containing whole rat spinal cord and complete Freund's adjuvant, presents clinical signs resembling the human disease.

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Induction

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