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Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo Video (Video) | JoVE

DOI :

10.3791/59249-v

March 26th, 2019

March 26th, 2019

7,249 Views

1Theodor Kocher Institute, University of Bern

Here, we present protocols to investigate impairment of the neurovascular unit during experimental autoimmune encephalomyelitis in vivo. We specifically address how to determine blood-brain barrier permeability and gelatinase activity involved in leukocyte migration across the glia limitans. 

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