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JoVE Journal

Immunology and Infection

This content is Open Access.

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

19.3K Views

06:45 min

December 18th, 2010

December 18th, 2010

19,274 Views

0:05

Title

1:02

Preparation of the Mouse

1:21

CASP Operation

3:12

Postoperative Care

3:26

CASPI

4:06

Postoperative Care

4:27

CASP and CASPI Clinical Outcomes

6:16

Conclusion

The Colon Ascendens Stent Peritonitis (CASP) is a highly standardized model for polymicrobial abdominal sepsis in rodents. This article describes the surgical procedure of CASP. The CASP model and its variants allow the systematic investigation of various problems concerning the subject of sepsis.

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