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JoVE Journal

Medicine

This content is Open Access.

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)

33.8K Views

12:43 min

February 21st, 2011

February 21st, 2011

33,806 Views

0:05

Title

0:55

Introduction

2:19

Respiratory Subsystem

5:05

Phonatory Subsystem

6:23

Resonatory Subsystem

7:10

Articulatory Subsystem: Face

8:10

Articulatory Subsystem: Tongue

9:22

System-level Assessment

9:58

Comprehensive Analyses of Bulbar Dysfunction in ALS

10:05

Case Study: Healthy Talkers vs. a Talker with ALS

Objective assessments of the physiological mechanisms that support speech are needed to monitor disease onset and progression in persons with ALS and to quantify treatment effects in clinical trials. In this video, we present a comprehensive, instrumentation-based protocol for quantifying speech motor performance in clinical populations.

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