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C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays

DOI :

10.3791/2490-v

9:58 min

March 11th, 2011

March 11th, 2011

28,080 Views

1Department of Molecular Biology, Lewis-Sigler Institute for Integrative Genomics, Princeton University, 2Lewis-Sigler Institute for Integrative Genomics, Princeton University

Here we describe methods to test C. elegans associative learning and short- and long-term associative memory. These population assays employ the worms abilities to chemotax toward volatile odorants, and form positive associations upon pairing food with the chemoattractant butanone. Increasing the number of conditioning periods induces long-term memory.

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C Elegans

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