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In vivo Bioluminescence Imaging of Tumor Hypoxia Dynamics of Breast Cancer Brain Metastasis in a Mouse Model

DOI :

10.3791/3175-v

October 3rd, 2011

October 3rd, 2011

19,180 Views

1Department of Radiation Oncology, University of Texas Southwestern Medical Center , 2Department of Radiology, University of Texas Southwestern Medical Center , 3Department of Radiation Oncology, Kyoto University Graduate School of Medicine

Bioluminescence imaging of hypoxia inducible factor-1α activity is applied to monitor intracranial tumor hypoxia development in a breast cancer brain metastasis mouse model.

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In Vivo Bioluminescence Imaging

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