In vivo Bioluminescent Imaging of Mammary Tumors Using IVIS Spectrum

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08:53 min

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April 29th, 2009

DOI :

April 29th, 2009

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Ed Lim¹, Kshitij D Modi¹, JaeBeom Kim¹

¹Biology Research and Development , Caliper Life Sciences

Transcript

Summary

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In Vivo Bioluminescent Imaging

4T1 Mouse Mammary Tumor Cells

Xenograft Tumor Model

Pre clinical Evaluation

Antitumor Compounds

Firefly Luciferase Gene

Luciferin Injection

Optical Imaging System

Absolute Quantitation

Longitudinal Studies

Tumor Growth Monitoring

Early Events In Tumor Development

Bioluminescent Signal Reduction

Tumor Cell Death

Chapters in this video

0:00

Title

0:48

Introduction

1:15

Cell Preparation

2:57

Animal Injection

4:06

Animal Imaging

6:27

Time Course

7:51

Conclusion

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