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An Orthotopic Mouse Model of Spontaneous Breast Cancer Metastasis

DOI :

10.3791/54040-v

August 14th, 2016

August 14th, 2016

27,658 Views

1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, 2Georgia Cancer Center, Augusta University, 3Charlie Norwood VA Medical Center

An orthotopic breast cancer primary tumor model and surgical removal of primary tumor to extend mouse life to generate spontaneous metastasis are described. The tumor growth and progression are monitored and quantified by luciferase fluorescence imaging.

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