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Directed Differentiation of Induced Pluripotent Stem Cells towards T Lymphocytes

DOI :

10.3791/3986-v

May 14th, 2012

May 14th, 2012

18,326 Views

1Department of Microbiology and Immunology, Pennsylvania State University College of Medicine

Generation of T lymphocytes from induced pluripotent stem (iPS) cells gives an alternative approach of using embryonic stem cells for T cell-based immunotherapy. The method shows that by utilizing either in vitro or in vivo induction system, iPS cells are able to differentiate into both conventional and antigen-specific T lymphocytes.

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Directed Differentiation

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