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In vivo Imaging of Tumor Angiogenesis using Fluorescence Confocal Videomicroscopy

DOI :

10.3791/50347-v

September 11th, 2013

September 11th, 2013

10,468 Views

1Université Paris Descartes Sorbonne Paris Cité, INSERM UMR-S970, 2Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Radiologie

In this paper, we present a method to analyze tumor microvessels in vivo using dynamic contrast-enhanced fluorescence videomicroscopy. Two quantitative parameters were acquired: functional capillary density reflecting the vascularity of the tumor, and index leakage reflecting the leakiness of the endothelial wall.

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