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In Vivo Imaging and Quantitation of the Host Angiogenic Response in Zebrafish Tumor Xenografts

DOI :

10.3791/59849-v

August 14th, 2019

August 14th, 2019

6,713 Views

1Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland

The aim of this method is to generate an in vivo model of tumor angiogenesis by xenografting mammalian tumor cells into a zebrafish embryo that has fluorescently-labelled blood vessels. By imaging the xenograft and associated vessels, a quantitative measurement of the angiogenic response can be obtained.

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In Vivo Imaging

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