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Photothrombotic Ischemia: A Minimally Invasive and Reproducible Photochemical Cortical Lesion Model for Mouse Stroke Studies

DOI :

10.3791/50370-v

June 9th, 2013

June 9th, 2013

33,105 Views

1Department of Neuroscience, University of Turin , 2Neuroscience Institute of Turin (NIT), University of Turin , 3Neuroscience Institute Cavalieri-Ottolenghi (NICO), University of Turin , 4Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin

Photothrombosis is a quick, minimally-invasive technique for inducing small and well-delimited infarction in areas of interest in highly reproducible manner. It is particularly suitable for studying cellular and molecular responses underlying brain plasticity in transgenic mice.

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