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Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells

DOI :

10.3791/50389-v

May 6th, 2013

May 6th, 2013

16,280 Views

1Department of Microbiology & Immunology, Pennsylvania State University College of Medicine

We provide a reproducible method to induce type 1 diabetes (T1D) in mice within two weeks by the adoptive transfer of islet antigen-specific, primary CD4+ T cells.

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