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Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance

DOI :

10.3791/3071-v

July 22nd, 2011

July 22nd, 2011

14,328 Views

1Department of Pediatrics/Allergy, Medical College of Wisconsin , 2Flow Cytometry Core Facility, Medical College of Wisconsin , 3Max McGee National Research Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin

Tregs are potent suppressors of the immune system. There is a lack of unique surface markers to define them, hence, definitions of Tregs are primarily functional. Here we describe an optimized in vitro assay capable of identifying immune imbalance in subjects at risk to develop T1D.

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Human In Vitro Suppression

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