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Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection

DOI :

10.3791/50964-v

12:30 min

November 22nd, 2013

November 22nd, 2013

39,239 Views

1Center for Molecular Bacteriology and Infection, Imperial College London

The larva of the wax moth Galleria mellonella was recently established as an in vivo model to study Legionella pneumophila infection. Here, we demonstrate fundamental techniques to characterize the pathogenesis of Legionella in the larvae, including inoculation, measurement of bacterial virulence and replication as well as extraction and analysis of infected hemocytes.

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Galleria Mellonella

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