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Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells

DOI :

10.3791/51737-v

September 15th, 2014

September 15th, 2014

16,089 Views

1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, 2Department of Obstetrics and Gynecology, Stanford University School of Medicine

We, based on knowledge from developmental biology and published research, developed an optimized protocol to efficiently generate A9 midbrain dopaminergic neurons from both human embryonic stem cells and human induced pluripotent stem cells, which would be useful for disease modeling and cell replacement therapy for Parkinson’s disease.

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