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Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

DOI :

10.3791/51827-v

August 22nd, 2014

August 22nd, 2014

13,936 Views

1Department of Pharmacology, Toxicology, & Neuroscience, Louisiana State University Health Sciences Center

Exercise may alleviate behavioral impairments associated with neurodegenerative diseases. Studies of the mechanisms underlying exercise-mediated effects have increased in disease models, but the neurobiological background accompanying these diseases, specifically aging, is likely not considered. Here, we illustrate measures to increase the likelihood of a successful exercise paradigm in aged rats.

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