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Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice

DOI :

10.3791/52197-v

9:05 min

May 4th, 2015

May 4th, 2015

26,122 Views

1Institute for Molecular Cardiovascular Research, RWTH Aachen University, Germany

A highly reproducible model for myocardial infarction in mice with minimal invasive manipulations is described. The model can be easily performed, resulting in a high reproducibility and survival rate. Thus, the described model will reduce the number of required animals as requested by the 3R principle (Replacement, Refinement and Reduction).

Tags

Minimal Invasive Surgical Procedure

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