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Rat Heterotopic Abdominal Heart/Single-lung Transplantation in a Volume-loaded Configuration

DOI :

10.3791/52418-v

May 29th, 2015

May 29th, 2015

8,143 Views

1Cardiovascular Surgery, UBC James Hogg Research Center, St. Paul's Hospital, 2Respiratory and Critical Care Medicine, UBC James Hogg Research Center, St. Paul's Hospital, 3UBC James Hogg Research Center, St. Paul's Hospital

We describe a novel technique for heterotopic abdominal heart-lung transplantation (HAHLT) in rats. The transplant configuration results in a partially loaded graft circulation, allowing direct functional assessment. This model may be employed for acute or chronic studies of function and immunologic status of the transplanted graft.

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