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Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells

12.2K Views

13:38 min

January 18th, 2017

DOI :

10.3791/54798-v

January 18th, 2017


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Aspirin fumarate Prodrug

Chapters in this video

0:05

Title

1:13

Synthesis of Aspirin-fumarate Prodrug, GTCpFE

6:10

Inhibiting the NFκB Activity with GTCpFE in Breast Cancer Cells

7:22

Inhibiting Breast Cancer Stem Cells with GTCpFE In Vitro

10:11

Results: GTCpFE Inhibits the NFκB Pathway, Mammosphere Formation, and the CD44+CD24- Immunophenotype in Breast Cancer Cells

11:49

Conclusion

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