JoVE Logo

Sign In

Acute and Chronic Models of Hyperglycemia in Zebrafish: A Method to Assess the Impact of Hyperglycemia on Neurogenesis and the Biodistribution of Radiolabeled Molecules

13.4K Views

13:35 min

June 26th, 2017

DOI :

10.3791/55203-v

June 26th, 2017


Explore More Videos

Zebrafish

Chapters in this video

0:00

Title

1:31

Establishing a Model of Acute Hyperglycemia in Zebrafish

2:59

Establishing a Model of Chronic Hyperglycemia in Zebrafish

3:41

Measuring Blood Glucose Levels in Zebrafish

5:00

Analyzing Brain Cell Proliferation Following Hyperglycemia

6:24

Sample Preparation for Immunohistochemistry

9:09

Microscopy

10:05

Studying the Impact of Hyperglycemia on Brain Repair Mechanism

11:08

Imaging the Bio-distribution of Radiolabeled Molecules by PET-Scan

12:28

Representative Results of [18F]-FDG PT/CT Imaging Distribution in Zebrafish

12:48

Conclusion

Related Videos

article

10:03

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

25.7K Views

article

05:20

Zebrafish Model of Neuroblastoma Metastasis

2.7K Views

article

07:55

The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System

3.8K Views

article

07:55

Simultaneous Calcium Imaging and Glucose Stimulation in Living Zebrafish to Investigate In Vivo β-Cell Function

1.7K Views

article

11:41

Real Time and Repeated Measurement of Skeletal Muscle Growth in Individual Live Zebrafish Subjected to Altered Electrical Activity

2.0K Views

article

06:46

Imaging Glycans in Zebrafish Embryos by Metabolic Labeling and Bioorthogonal Click Chemistry

13.6K Views

article

10:01

Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain

11.2K Views

article

10:07

Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tg(fli:EGFP) Zebrafish Retinal Vasculature

13.2K Views

article

05:49

Alternate Immersion in Glucose to Produce Prolonged Hyperglycemia in Zebrafish

4.8K Views

article

08:35

High Throughput Danio Rerio Energy Expenditure Assay

12.6K Views

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2025 MyJoVE Corporation. All rights reserved