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A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

DOI :

10.3791/55383-v

May 25th, 2017

May 25th, 2017

8,799 Views

1Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, 2Department of Electrical and Computer Engineering, University of Houston

Antibiotic efficacy is most commonly determined by conducting killing kinetic studies and measuring colony forming units (CFUs). By integrating scanning electron microscopy (SEM) with these standard methods, we can distinguish the pharmacological effects of treatment between different antibiotics.

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