JoVE Logo
Faculty Resource Center

Sign In

An In Vitro Organ Culture Model of the Murine Intervertebral Disc

DOI :

10.3791/55437-v

April 11th, 2017

April 11th, 2017

9,126 Views

1Department of Biomedical Engineering, Washington University in St. Louis, 2Department of Biology, Washington University in St. Louis, 3Department of Orthopaedic Surgery, Washington University in St. Louis, 4Department of Materials Science and Mechanical Engineering, Washington University in St. Louis

Whole organ culture of the intervertebral disc (IVD) preserves the native extracellular matrix, cell phenotypes, and cellular-matrix interactions. Here we describe an IVD culture system using mouse lumbar and caudal IVDs in their functional spinal units and several applications utilizing this system.

Tags

In Vitro Organ Culture Model

-- Views

Related Videos

article

Alginate Hydrogels for Three-Dimensional Organ Culture of Ovaries and Oviducts

article

Preparation of Intact Bovine Tail Intervertebral Discs for Organ Culture

article

Silk Film Culture System for in vitro Analysis and Biomaterial Design

article

Tissue Engineering of the Intestine in a Murine Model

article

In vitro Cell Culture Model for Toxic Inhaled Chemical Testing

article

Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model

article

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

article

Decellularization of Whole Human Heart Inside a Pressurized Pouch in an Inverted Orientation

article

A Human 3D Extracellular Matrix-Adipocyte Culture Model for Studying Matrix-Cell Metabolic Crosstalk

article

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved