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Preparation Steps for Measurement of Reactivity in Mouse Retinal Arterioles Ex Vivo

DOI :

10.3791/56199-v

May 8th, 2018

May 8th, 2018

6,954 Views

1Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz

Many vision-threatening ocular diseases are associated with dysfunctional retinal microvessels. Therefore, the measurement of retinal arteriole responses is important to investigate the underlying pathophysiological mechanisms. This article describes a detailed protocol for mouse retinal arteriole isolation and preparation to assess the effects of vasoactive substances on vascular diameter.

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Measurement

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