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Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle

DOI :

10.3791/56201-v

October 26th, 2017

October 26th, 2017

9,276 Views

1Cellular Plasticity & Disease Modelling, Department of Developmental & Stem Cell Biology, CNRS UMR 3738, Institut Pasteur

Here we present a detailed protocol to detect both senescent and pluripotent stem cells in the skeletal muscle upon injury while inducing in vivo reprogramming. This method is suitable for evaluating the role of cellular senescence during tissue regeneration and reprogramming in vivo.

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Injury induced Senescence

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