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Isometric Contractility Measurement of the Mouse Mesenteric Artery Using Wire Myography

DOI :

10.3791/58064-v

August 20th, 2018

August 20th, 2018

13,893 Views

1Model Animal Research Center and MOE Key Laboratory of Model Animal and Disease Study, Nanjing University, 2School of Pharmacy, Nanjing University of Chinese Medicine

The wire myograph technique is used to investigate vascular smooth muscle functions and screen new drugs. We report a detailed protocol for measuring the isometric contractility of the mouse mesenteric artery and for screening new relaxants of vascular smooth muscle.

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