JoVE Logo
Faculty Resource Center

Sign In

A Simple Critical-sized Femoral Defect Model in Mice

DOI :

10.3791/52368-v

March 15th, 2015

March 15th, 2015

14,750 Views

1Institute for Regenerative Medicine at Scott & White Hospital, Texas A&M Health Science Center, 2Department of Orthopedic Surgery, University of Texas Medical Branch, 3Molecular and Cellular Medicine, Texas A&M Health Science Center

Animal models are frequently employed to mimic serious bone injury in biomedical research. Due to their small size, establishment of stabilized bone lesions in mice are beyond the capabilities of most research groups. Herein, we describe a simple method for establishing and analyzing experimental femoral defects in mice.

Tags

Critical sized Femoral Defect Model

-- Views

Related Videos

article

A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice

article

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

article

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate

article

A Simple Method of Mouse Lung Intubation

article

Femoral Bone Marrow Aspiration in Live Mice

article

Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice

article

A Murine Model of Arterial Restenosis: Technical Aspects of Femoral Wire Injury

article

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

article

A Repetitive Concussive Head Injury Model in Mice

article

The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved