JoVE Logo
Faculty Resource Center

Sign In

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation Video (Video) | JoVE

DOI :

10.3791/58332-v

October 12th, 2018

October 12th, 2018

7,588 Views

1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine

Here, we present a protocol to quickly and reproducibly generate biologically inspired, biodegradable articifical antigen presenting cells (aAPC) with tunable size, shape, and surface protein presentation for T cell expansion ex vivo or in vivo.

-- Views

Related Videos

article

Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil Video (Video) | JoVE

article

Measuring Fluxes of Mineral Nutrients and Toxicants in Plants with Radioactive Tracers Video (Video) | JoVE

article

A Whole Cell Bioreporter Approach to Assess Transport and Bioavailability of Organic Contaminants in Water Unsaturated Systems Video (Video) | JoVE

article

Use of Chironomidae Diptera Surface-Floating Pupal Exuviae as a Rapid Bioassessment Protocol for Water Bodies Video (Video) | JoVE

article

Extraction of Structural Extracellular Polymeric Substances from Aerobic Granular Sludge Video (Video) | JoVE

article

Functionalization and Dispersion of Carbon Nanomaterials Using an Environmentally Friendly Ultrasonicated Ozonolysis Process Video (Video) | JoVE

article

Ecosystem Fabrication EcoFAB Protocols for The Construction of Laboratory Ecosystems Designed to Study Plant-microbe Interactions Video (Video) | JoVE

article

A Strain Gauge Monitor SGM for Continuous Valve Gape Measurements in Bivalve Molluscs in Response to Laboratory Induced Diel-cycling Hypoxia and pH Video (Video) | JoVE

article

Bioindication Testing of Stream Environment Suitability for Young Freshwater Pearl Mussels Using In Situ Exposure Methods Video (Video) | JoVE

article

Cultivation of Green Microalgae in Bubble Column Photobioreactors and an Assay for Neutral Lipids Video (Video) | JoVE

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved