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Artificial Antigen Presenting Cell (aAPC) Mediated Activation and Expansion of Natural Killer T Cells

DOI :

10.3791/4333-v

13:18 min

December 29th, 2012

December 29th, 2012

17,489 Views

1Department of Microbiology and Immunology, University of Maryland

Here we describe a method for activating and expanding human NKT cells from bulk T cell populations using artificial antigen presenting cells (aAPC). The use of CD1d-based aAPC provides a standardized method for generating high numbers of functional NKT cells.

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Artificial Antigen Presenting Cell aAPC

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