Pancreatic Tissue-Derived Extracellular Matrix Bioink for Printing 3D Cell-Laden Pancreatic Tissue Constructs

10.8K Views

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07:55 min

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December 13th, 2019

DOI :

10.3791/60434-v

December 13th, 2019

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Jaewook Kim*¹, Myungji Kim*², Dong Gyu Hwang², In Kyong Shim³, Song Cheol Kim³^,⁴, Jinah Jang¹^,²^,⁵

¹Department of Mechanical Engineering, Pohang University of Science and Technology, ²School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, ³Asan Institute for Life Science, University of Ulsan College of Medicine and Asan Medical Center, ⁴Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, ⁵Department of Creative IT Engineering, Pohang University of Science and Technology

Summary

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PdECM Bioink

Extracellular Matrix

3D Printing

Pancreatic Tissue Construct

Islet Encapsulation

Tissue specific Components

Decellularization

Porcine Pancreas

Type One Diabetes

Transplantable Constructs

In Vitro Models

Diabetes Complications

Pancreatic Cancer

Lyophilization

Chapters in this video

0:04

Title

1:10

Tissue Decellularization

2:50

Pancreatic Tissue Derived Decellularized Extracellular Matrix (pdECM) Bioink Preparation

3:45

3D Pancreatic Construct Cell Printing with Patterned Structure

5:11

Results: Representative Biochemical Characterization and Rheological Analysis of pdECM Bioink

6:50

Conclusion

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