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Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

DOI :

10.3791/60825-v

March 12th, 2020

March 12th, 2020

10,326 Views

1Department of Organic Chemistry, Institute of Chemistry, University of Campinas (UNICAMP), 2Center for Natural and Human Sciences, Federal University of ABC (UFABC)

A mass spectrometry-guided genome mining protocol is established and described here. It is based on genome sequence information and LC-MS/MS analysis and aims to facilitate identification of molecules from complex microbial and plant extracts.

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