JoVE Journal

Bioengineering

This content is Open Access.

Primary Clarification of CHO Harvested Cell Culture Fluid using an Acoustic Separator

Presented here is a protocol for the primary clarification of CHO cell culture using an acoustic separator. This protocol can be used for the primary clarification of shake flask cultures or bioreactor harvests and has the potential application for continuous clarification of the cell bleed material during perfusion bioreactor operations.

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