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An Improved Assay and Tools for Measuring Mechanical Nociception in Drosophila Larvae

DOI :

10.3791/61911-v

7:17 min

October 29th, 2020

October 29th, 2020

4,261 Views

1Department of Genetics, The University of Texas MD Anderson Cancer Center, 2Neuroscience Graduate Program, Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, 3Genetics and Epigenetics Graduate Program, Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center

The goal of this protocol is to show how to perform an improved assay for mechanical nociception in Drosophila larvae. We use the assay here to demonstrate that mechanical hypersensitivity (allodynia and hyperalgesia) exists in Drosophila larvae.

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Mechanical Nociception

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