A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes

2.8K Views

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07:37 min

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October 28th, 2021

DOI :

10.3791/62445-v

October 28th, 2021

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2,776 Views

Yong Gyu Lee¹^,², Jung-Lye Kim¹^,², Andre F. Palmer³, Brenda F. Reader⁴, Jianjie Ma¹, Sylvester M. Black²^,⁴, Bryan A. Whitson¹^,²

¹Department of Surgery Division of Cardiac Surgery, The Ohio State University Wexner Medical Center, ²The Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Laboratory, The Ohio State University College of Medicine, ³William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering, The Ohio State University, ⁴Comprehensive Transplant Center, The Ohio State University Wexner Medical Center

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Summary

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Rat Lung Transplantation

Warm Ischemia reperfusion Injury

Endotracheal Intubation

Heparin Administration

Molecular Mechanisms

Therapeutic Interventions

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