Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation

DOI :

10.3791/635-v

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December 31st, 2007

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9,793 Views

Mitchell Kronenberg¹

¹Department of Developmental Immunology, La Jolla Institute for Allergy and Immunology

Chapters

Natural Killer T cells (NKT) are critical determinants of the immune response to cancer, regulation of autioimmunity, clearance of infection, and the development of artheriosclerotic plaques. In this interview, Mitch Kronenberg discusses his laboratory's efforts to understand the mechanism through which NKT cells are activated by glycolipid antigens.