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Christopher Hughes: An in vitro model for the Study of Angiogenesis Interview Video (Video) | JoVE

DOI :

10.3791/175-v

April 28th, 2007

April 28th, 2007

8,375 Views

1Department of Molecular Biology and Biochemistry, University of California, Irvine (UCI)

Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro. He explains the importance of fibroblasts that secrete a critical, yet unidentified, soluble factor that allow endothelial cells to form vessels in culture that branch, form proper lumens, and undergo anastamosis.

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