Application of Unsupervised Multi-Omic Factor Analysis to Uncover Patterns of Variation and Molecular Processes Linked to Cardiovascular Disease
1.1K Views
•
08:51 min
•
September 20th, 2024
DOI :
September 20th, 2024
•Corinna Losert1,2, Kami Pekayvaz3,4, Viktoria Knottenberg3,4, Leo Nicolai3,4, Konstantin Stark3,4, Matthias Heinig1,2,4
1Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, 2Department of Computer Science, TUM School of Computation, Information and Technology, Technical University of Munich, 3Medizinische Klinik und Poliklinik I University Hospital Ludwig-Maximilian University, 4German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance
Explore More Videos
Chapters in this video
0:00
Introduction
1:27
Preparation, Pre‐Processing, and Harmonization of Data for MOFA Analysis
5:35
Running MOFA for Unsupervised Data Exploration of Complex Multi‐Omics Datasets
Related Videos
10:40
Analysis of Cap-binding Proteins in Human Cells Exposed to Physiological Oxygen Conditions
7.7K Views
10:39
Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase II
15.4K Views
12:54
Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation
13.4K Views
06:11
Production and Purification of Baculovirus for Gene Therapy Application
14.7K Views
07:59
An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
7.6K Views
09:34
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
33.5K Views
09:34
A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
6.6K Views
09:43
Multimodal Study of Murine Cardiovascular Remodeling: Four-Dimensional Ultrasound and Mass Spectrometry Imaging
661 Views
08:21
Intradermal Microdialysis: An Approach to Investigating Novel Mechanisms of Microvascular Dysfunction in Humans
1.2K Views
09:47
DeepOmicsAE: Representing Signaling Modules in Alzheimer's Disease with Deep Learning Analysis of Proteomics, Metabolomics, and Clinical Data
942 Views
Copyright © 2025 MyJoVE Corporation. All rights reserved