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Isolation and Analysis of Hematopoietic Stem Cells from the Placenta

DOI :

10.3791/742-v

June 24th, 2008

June 24th, 2008

19,903 Views

1Jonsson Comprehensive Cancer Center, University of California, Los Angeles

We have identified the placenta as a major hematopoietic organ during development. We found that hematopoietic stem cells (HSCs) are both generated and expanded in the placenta in unique microenvironmental niches. Here, we describe experimental techniques required for isolation and visualization of HSCs in the mouse placenta.

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