Francisco Fernandez-Lima

Chemistry and Biochemistry, Florida International University

Affiliated withFlorida International University

Research Area

EnvironmentEcologyChemistry

Biography

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JoVE Journal Publications

Article Total : 4	Year
Publication title	2017
Publication title	2024
Publication title	2024
Publication title	2024

Other Publications

Article	Year
Characterization of (NH3)(n=1-6)NH+ clusters produced by 252Cf fragments impact onto a NH3 condensed target. The journal of physical chemistry. A\| PubMed ID: 17685500	2007
Ion mobility-mass spectrometer interface for collisional activation of mobility separated ions. Analytical chemistry\| PubMed ID: 19072664	2009
A novel approach to collision-induced dissociation (CID) for ion mobility-mass spectrometry experiments. Journal of the American Society for Mass Spectrometry\| PubMed ID: 19135385	2009
A new copper containing MALDI matrix that yields high abundances of [peptide + Cu]+ ions. Journal of the American Society for Mass Spectrometry\| PubMed ID: 19318231	2009
Theoretical and experimental study of negative LiF clusters produced by fast ion impact on a polycrystalline 7LiF target. The journal of physical chemistry. A\| PubMed ID: 19685887	2009
Petroleum crude oil characterization by IMS-MS and FTICR MS. Analytical chemistry\| PubMed ID: 19904990	2009
Amino acid influence on copper binding to peptides: cysteine versus arginine. Journal of the American Society for Mass Spectrometry\| PubMed ID: 20138783	2010
A Study of Ion-Neutral Collision Cross Section Values for Low Charge States of Peptides, Proteins, and Peptide/Protein Complexes. International journal of mass spectrometry\| PubMed ID: 21503273	2010
Analysis of native biological surfaces using a 100 kV massive gold cluster source. Analytical chemistry\| PubMed ID: 21967684	2011
Analysis of Fluorescent Proteins with a Nanoparticle Probe. The journal of physical chemistry letters\| PubMed ID: 22308203	2012
Alkali halide clusters produced by fast ion impact. Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms\| PubMed ID: 22389542	2012
Bi-Directional Ion Emission from Massive Gold Cluster Impacts on Nanometric Carbon Foils. The journal of physical chemistry. C, Nanomaterials and interfaces\| PubMed ID: 22888385	2012
Gas-phase separation using a trapped ion mobility spectrometer. International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry\| PubMed ID: 24163587	2011
Isomerization kinetics of AT hook decapeptide solution structures. Analytical chemistry\| PubMed ID: 24364733	2014
Alkali Halide Nanotubes: Structure and Stability. The journal of physical chemistry. C, Nanomaterials and interfaces\| PubMed ID: 24376901	2012
Direct observation of differences of carotenoid polyene chain cis/trans isomers resulting from structural topology. Analytical chemistry\| PubMed ID: 24428664	2014
Ion dynamics in a trapped ion mobility spectrometer. The Analyst\| PubMed ID: 24571000	2014
Secondary ion mass spectrometry imaging of Dictyostelium discoideum aggregation streams. PloS one\| PubMed ID: 24911189	2014
Flavin adenine dinucleotide structural motifs: from solution to gas phase. Analytical chemistry\| PubMed ID: 25222439	2014
Changes in lipid distribution in E. coli strains in response to norfloxacin. Journal of mass spectrometry : JMS\| PubMed ID: 25601679	2015
Kinetic intermediates of holo- and apo-myoglobin studied using HDX-TIMS-MS and molecular dynamic simulations. Journal of the American Society for Mass Spectrometry\| PubMed ID: 25690175	2015
Targeted high-resolution ion mobility separation coupled to ultrahigh-resolution mass spectrometry of endocrine disruptors in complex mixtures. Analytical chemistry\| PubMed ID: 25818070	2015
The Dimerization State of the Mammalian High Mobility Group Protein AT-Hook 2 (HMGA2). PloS one\| PubMed ID: 26114780	2015
Lifetimes and stabilities of familiar explosive molecular adduct complexes during ion mobility measurements. The Analyst\| PubMed ID: 26153567	2015
Towards unsupervised polyaromatic hydrocarbons structural assignment from SA-TIMS-FTMS data. International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry\| PubMed ID: 26525904	2015
Characterization of the Photophysical, Thermodynamic, and Structural Properties of the Terbium(III)-DREAM Complex. Biochemistry\| PubMed ID: 26901070	2016
Increasing Polyaromatic Hydrocarbon (PAH) Molecular Coverage during Fossil Oil Analysis by Combining Gas Chromatography and Atmospheric-Pressure Laser Ionization Fourier Transform Ion Cyclot... Energy & fuels : an American Chemical Society journal\| PubMed ID: 27212790	2016
Theoretical predictor for candidate structure assignment from IMS data of biomolecule-related conformational space. International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry\| PubMed ID: 27330407	2015
Oversampling Selective Accumulation Trapped Ion Mobility Spectrometry Coupled to FT-ICR MS: Fundamentals and Applications. Analytical chemistry\| PubMed ID: 27340830	2016
Fast, ultra-trace detection of juvenile hormone III from mosquitoes using mass spectrometry. Talanta\| PubMed ID: 27474320	2016
Analysis of Chemotherapeutic Drug Delivery at the Single Cell Level Using 3D-MSI-TOF-SIMS. Journal of the American Society for Mass Spectrometry\| PubMed ID: 27582118	2016
Isomer Separation of Polybrominated Diphenyl Ether Metabolites using nanoESI-TIMS-MS. International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry\| PubMed ID: 27642261	2016
Lipid specific molecular ion emission as a function of the primary ion characteristics in TOF-SIMS. Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B\| PubMed ID: 27648391	2016
Structures of the kinetically trapped i-motif DNA intermediates. Physical chemistry chemical physics : PCCP\| PubMed ID: 27711445	2016
Towards the Analysis of High Molecular Weight Proteins and Protein complexes using TIMS-MS. International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry\| PubMed ID: 27818614	2016
Analysis of Photoirradiated Water Accommodated Fractions of Crude Oils Using Tandem TIMS and FT-ICR MS. Environmental science & technology\| PubMed ID: 28457132	2017
Characterization of Intramolecular Interactions of Cytochrome c Using Hydrogen-Deuterium Exchange-Trapped Ion Mobility Spectrometry-Mass Spectrometry and Molecular Dynamics. Analytical chemistry\| PubMed ID: 28742962	2017
Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS. Journal of the American Society for Mass Spectrometry\| PubMed ID: 28889248	2018
Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac. Scientific reports\| PubMed ID: 28894190	2017
Fast and Effective Ion Mobility-Mass Spectrometry Separation of d-Amino-Acid-Containing Peptides. Analytical chemistry\| PubMed ID: 28982001	2017
Publisher Correction: Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac. Scientific reports\| PubMed ID: 29162895	2017
Linear and Differential Ion Mobility Separations of Middle-Down Proteoforms. Analytical chemistry\| PubMed ID: 29359922	2018
Increasing Analytical Separation and Duty Cycle with Nonlinear Analytical Mobility Scan Functions in TIMS-FT-ICR MS. Analytical chemistry\| PubMed ID: 29376337	2018
Insights from ion mobility-mass spectrometry, infrared spectroscopy, and molecular dynamics simulations on nicotinamide adenine dinucleotide structural dynamics: NADvs. NADH. Physical chemistry chemical physics : PCCP\| PubMed ID: 29473073	2018
JH biosynthesis and hemolymph titers in adult male Aedes aegypti mosquitoes. Insect biochemistry and molecular biology\| PubMed ID: 29526769	2018
Analysis of isomeric opioids in urine using LC-TIMS-TOF MS. Talanta\| PubMed ID: 29567161	2018
Identification of Lasso Peptide Topologies Using Native Nanoelectrospray Ionization-Trapped Ion Mobility Spectrometry-Mass Spectrometry. Analytical chemistry\| PubMed ID: 29579382	2018
Metal ions induced secondary structure rearrangements: mechanically interlocked lasso vs. unthreaded branched-cyclic topoisomers. The Analyst\| PubMed ID: 29721555	2018
Biochemical Basis of Topoisomerase I Relaxation Activity Reduction by Nonenzymatic Lysine Acetylation. International journal of molecular sciences\| PubMed ID: 29751635	2018
Coupling trapped ion mobility spectrometry to mass spectrometry: trapped ion mobility spectrometry-time-of-flight mass spectrometry versus trapped ion mobility spectrometry-Fourier transform... Rapid communications in mass spectrometry : RCM\| PubMed ID: 29756663	2018
Discovery and targeted monitoring of polychlorinated biphenyl metabolites in blood plasma using LC-TIMS-TOF MS. International journal of mass spectrometry\| PubMed ID: 29915519	2018
Peptide Sequence Influence on the Conformational Dynamics and DNA binding of the Intrinsically Disordered AT-Hook 3 Peptide. Scientific reports\| PubMed ID: 30018295	2018
The effects of solution additives and gas-phase modifiers on the molecular environment and conformational space of common heme proteins. Rapid communications in mass spectrometry : RCM\| PubMed ID: 30421840	2019
Single-stranded DNA structural diversity: TAGGGT from monomers to dimers to tetramer formation. Rapid communications in mass spectrometry : RCM\| PubMed ID: 30506977	2019
Structural signatures of the class III lasso peptide BI-32169 and the branched-cyclic topoisomers using trapped ion mobility spectrometry-mass spectrometry and tandem mass spectrometry. Analytical and bioanalytical chemistry\| PubMed ID: 30707269	2019
Recommendations for reporting ion mobility Mass Spectrometry measurements. Mass spectrometry reviews\| PubMed ID: 30707468	2019
Juvenile hormone controls ovarian development in female Anopheles albimanus mosquitoes. Scientific reports\| PubMed ID: 30765796	2019
Measuring the Integrity of Gas-Phase Conformers of Sodiated 25-Hydroxyvitamin D3 by Drift Tube, Traveling Wave, Trapped, and High-Field Asymmetric Ion Mobility. Analytical chemistry\| PubMed ID: 30807105	2019
Evidence of Cis/Trans-Isomerization at Pro7/Pro16 in the Lasso Peptide Microcin J25. Journal of the American Society for Mass Spectrometry\| PubMed ID: 30834511	2019
Microheterogeneity of Topoisomerase IA/IB and Their DNA-Bound States. ACS omega\| PubMed ID: 30842985	2019
Effective Liquid Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry Separation of Isomeric Lipid Species. Analytical chemistry\| PubMed ID: 30896930	2019
Understanding the structural complexity of dissolved organic matter: isomeric diversity. Faraday discussions\| PubMed ID: 31134248	2019
Inhibition of juvenile hormone synthesis in mosquitoes by the methylation inhibitor 3-deazaneplanocin A (DZNep). Insect biochemistry and molecular biology\| PubMed ID: 31265905	2019
Exploring the Conformational Space of Growth-Hormone-Releasing Hormone Analogues Using Dopant Assisted Trapped Ion Mobility Spectrometry-Mass Spectrometry. The journal of physical chemistry. B\| PubMed ID: 31299151	2019
Dynamics of the E. coli β-Clamp Dimer Interface and Its Influence on DNA Loading. Biophysical journal\| PubMed ID: 31349986	2019
Structural Motif Descriptors as a Way To Elucidate the Agonistic or Antagonistic Activity of Growth Hormone-Releasing Hormone Peptide Analogues. ACS omega\| PubMed ID: 31458901	2018
Three Dimensional Secondary Ion Mass Spectrometry Imaging (3D-SIMS) of ovarian follicles. Journal of analytical atomic spectrometry\| PubMed ID: 31680712	2019
Common structural features facilitate the simultaneous identification and quantification of the five most common juvenile hormones by liquid chromatography-tandem mass spectrometry. Insect biochemistry and molecular biology\| PubMed ID: 31760138	2020
Multimodal, in Situ Imaging of Ex Vivo Human Skin Reveals Decrease of Cholesterol Sulfate in the Neoepithelium during Acute Wound Healing. Analytical chemistry\| PubMed ID: 31789498	2020
The juvenile hormone described in Rhodnius prolixus by Wigglesworth is juvenile hormone III skipped bisepoxide. Scientific reports\| PubMed ID: 32080221	2020
LESA Cyclic Ion Mobility Mass Spectrometry of Intact Proteins from Thin Tissue Sections. Analytical chemistry\| PubMed ID: 32271006	2020
Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype. Frontiers in cardiovascular medicine\| PubMed ID: 32509802	2020
Following Structural Changes by Thermal Denaturation Using Trapped Ion Mobility Spectrometry-Mass Spectrometry. The journal of physical chemistry. B\| PubMed ID: 32560586	2020
Mapping chemotherapeutic drug distribution in cancer cell spheroids using 2D-TOF-SIMS and LESA-TIMS-MS. The Analyst\| PubMed ID: 32966375	2020
Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays. Scientific reports\| PubMed ID: 33139812	2020
Trapped Ion Mobility Spectrometry of Native Macromolecular Assemblies. Analytical chemistry\| PubMed ID: 33492949	2021
Structural Insights from Tandem Mass Spectrometry, Ion Mobility-Mass Spectrometry, and Infrared/Ultraviolet Spectroscopy on Sphingonodin I: Lasso vs Branched-Cyclic Topoisomers. Journal of the American Society for Mass Spectrometry\| PubMed ID: 33765377	2021
Comprehensive Screening of Polycyclic Aromatic Hydrocarbons and Similar Compounds Using GC-APLI-TIMS-TOFMS/GC-EI-MS. Analytical chemistry\| PubMed ID: 33835784	2021
Following de novo triglyceride dynamics in ovaries of Aedes aegypti during the previtellogenic stage. Scientific reports\| PubMed ID: 33953286	2021
Structural Heterogeneity of Human Histone H2A.1. The journal of physical chemistry. B\| PubMed ID: 33974801	2021
Exploring structural signatures of the lanthipeptide prochlorosin 2.8 using tandem mass spectrometry and trapped ion mobility-mass spectrometry. Analytical and bioanalytical chemistry\| PubMed ID: 34105020	2021
Proteoform Differentiation using Tandem Trapped Ion Mobility, Electron Capture Dissociation, and ToF Mass Spectrometry. Analytical chemistry\| PubMed ID: 34170114	2021
Author Correction: Following de novo triglyceride dynamics in ovaries of Aedes aegypti during the previtellogenic stage. Scientific reports\| PubMed ID: 34354221	2021
A Bifunctional Leader Peptidase/ABC Transporter Protein Is Involved in the Maturation of the Lasso Peptide Cochonodin I from . Journal of natural products\| PubMed ID: 34597519	2021
Epoxidation of juvenile hormone was a key innovation improving insect reproductive fitness. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 34697248	2021
Effective discrimination of gas-phase peptide conformers using TIMS-ECD-ToF MS/MS. Analytical methods : advancing methods and applications\| PubMed ID: 34698320	2021
Substrate Sequence Controls Regioselectivity of Lanthionine Formation by ProcM. Journal of the American Chemical Society\| PubMed ID: 34724611	2021
Structural Characterization of Human Histone H4.1 by Tandem Nonlinear and Linear Ion Mobility Spectrometry Complemented with Molecular Dynamics Simulations. ACS omega\| PubMed ID: 34778628	2021
Unsupervised Structural Classification of Dissolved Organic Matter Based on Fragmentation Pathways. Environmental science & technology\| PubMed ID: 34981937	2022
Sexual dimorphism of diapause regulation in the hemipteran bug Pyrrhocoris apterus. Insect biochemistry and molecular biology\| PubMed ID: 35007710	2022
AT-hook peptides bind the major and minor groove of AT-rich DNA duplexes. Nucleic acids research\| PubMed ID: 35212375	2022
Spatially Resolved Neuropeptide Characterization from Neuropathological Formalin-Fixed, Paraffin-Embedded Tissue Sections by a Combination of Imaging MALDI FT-ICR Mass Spectrometry Histochem... Journal of the American Society for Mass Spectrometry\| PubMed ID: 35258288	2022
Coupling Stable Isotope Labeling and Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight-Tandem Mass Spectrometry for Mosquito Ovarian Lipid Studies. Analytical chemistry\| PubMed ID: 35420029	2022
Salt bridges govern the structural heterogeneity of heme protein interactions and porphyrin networks: microperoxidase-11. RSC advances\| PubMed ID: 35519052	2020
Nanomolar affinity of EF-hands in neuronal calcium sensor 1 for bivalent cations Pb2+, Mn2+, and Hg2. Metallomics : integrated biometal science\| PubMed ID: 35657675	2022
Trapped Ion Mobility Spectrometry, Ultraviolet Photodissociation, and Time-of-Flight Mass Spectrometry for Gas-Phase Peptide Isobars/Isomers/Conformers Discrimination. Journal of the American Society for Mass Spectrometry\| PubMed ID: 35658468	2022
Exploring the Conformational and Binding Dynamics of HMGA2·DNA Complexes Using Trapped Ion Mobility Spectrometry-Mass Spectrometry. Journal of the American Society for Mass Spectrometry\| PubMed ID: 35687119	2022
Exploring the Conformations and Binding Location of HMGA2·DNA Complexes Using Ion Mobility Spectrometry and 193 nm Ultraviolet Photodissociation Mass Spectrometry. Journal of the American Society for Mass Spectrometry\| PubMed ID: 35687872	2022
Globin X: A highly stable intrinsically hexacoordinate globin. Journal of inorganic biochemistry\| PubMed ID: 36058051	2022
Top-"Double-Down" Mass Spectrometry of Histone H4 Proteoforms: Tandem Ultraviolet-Photon and Mobility/Mass-Selected Electron Capture Dissociations. Analytical chemistry\| PubMed ID: 36282112	2022
Large-Scale Interlaboratory DI-FT-ICR MS Comparability Study Employing Various Systems. Journal of the American Society for Mass Spectrometry\| PubMed ID: 36371691	2022
Genetics tools for corpora allata specific gene expression in Aedes aegypti mosquitoes. Scientific reports\| PubMed ID: 36443489	2022
Crosstalk between Nutrition, Insulin, Juvenile Hormone, and Ecdysteroid Signaling in the Classical Insect Model, . International journal of molecular sciences\| PubMed ID: 36613451	2022
Description of Dissolved Organic Matter Transformational Networks at the Molecular Level. Environmental science & technology\| PubMed ID: 36724500	2023
Submicron 3-D mass spectrometry imaging reveals an asymmetric molecular distribution on chemotaxing cells. F1000Research\| PubMed ID: 36845326	2022
Distinct mechanism of Tb and Eu binding to NCS1. Physical chemistry chemical physics : PCCP\| PubMed ID: 36938969	2023
Anticancer Drug Doxorubicin Spontaneously Reacts with GTP and dGTP. Chemical research in toxicology\| PubMed ID: 37000908	2023
Integration of Trapped Ion Mobility Spectrometry and Ultraviolet Photodissociation in a Quadrupolar Ion Trap Mass Spectrometer. Analytical chemistry\| PubMed ID: 37220214	2023
Effects of mating on female reproductive physiology in the insect model, Rhodnius prolixus, a vector of the causative parasite of Chagas disease. PLoS neglected tropical diseases\| PubMed ID: 37729234	2023
HIV-1 and opiates modulate miRNA profiles in extracellular vesicles. Frontiers in immunology\| PubMed ID: 38022533	2023
Top/Middle-Down Characterization of α-Synuclein Glycoforms. Analytical chemistry\| PubMed ID: 38047498	2023
An Integrated Metabolomics-Based Model, and Identification of Potential Biomarkers, of Perfluorooctane Sulfonic Acid Toxicity in Zebrafish Embryos. Environmental toxicology and chemistry\| PubMed ID: 38411227	2024
Conjugating Daunorubicin and Doxorubicin to GTP by Formaldehyde to Overcome Drug Resistance. ChemMedChem\| PubMed ID: 39136598	2024
Bottom-up Histone Post-translational Modification Analysis using Liquid Chromatography, Trapped Ion Mobility Spectrometry, and Tandem Mass Spectrometry. Journal of proteome research\| PubMed ID: 39177337	2024
Conformational and Structural Characterization of Knotted Proteins. Biochemistry\| PubMed ID: 39189377	2024
Top-Down Structural Characterization of Native Ubiquitin Combining Solution-Stable Isotope Labeling, Trapped Ion Mobility Spectrometry, and Tandem Electron Capture Dissociation Mass Spectrom... Analytical chemistry\| PubMed ID: 39214608	2024
Gas-Phase Structures of Fucosylated Oligosaccharides: Alkali Metal and Halogen Influences. The journal of physical chemistry. B\| PubMed ID: 39226480	2024
Revisiting Dissolved Organic Matter Analysis Using High-Resolution Trapped Ion Mobility and FT-ICR Mass Spectrometry. Journal of the American Society for Mass Spectrometry\| PubMed ID: 39265105	2024
Online, Bottom-up Characterization of Histone H4 4-17 Isomers. Analytical chemistry\| PubMed ID: 39422312	2024