Milena Z. Adzemovic

Department of Clinical Neuroscience,
Neuroimmunology Unit,
Center for Molecular Medicine,
Centre for Molecular Medicine,
Department of Clinical Neuroscience, Neuroimmunology Unit, Center for Molecular Medicine,
Centre for Molecular Medicine, Department of Clinical Neuroscience

Karolinska Institutet

BIOGRAPHY

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PUBLICATIONS

Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat.

PloS one Sep, 2010 | Pubmed ID: 20856809

IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation.

Journal of immunology (Baltimore, Md. : 1950) Dec, 2010 | Pubmed ID: 21041731

Expression of Ccl11 associates with immune response modulation and protection against neuroinflammation in rats.

PloS one , 2012 | Pubmed ID: 22815714

Imatinib ameliorates neuroinflammation in a rat model of multiple sclerosis by enhancing blood-brain barrier integrity and by modulating the peripheral immune response.

PloS one , 2013 | Pubmed ID: 23437178

Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage.

Experimental neurology Nov, 2013 | Pubmed ID: 23954214

Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats.

Neurobiology of disease Nov, 2014 | Pubmed ID: 25149263

Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells.

Journal of the National Cancer Institute Oct, 2015 | Pubmed ID: 26296362

Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration.

Acta neuropathologica Mar, 2016 | Pubmed ID: 26687981

Expression of vascular endothelial growth factor (VEGF)-B and its receptor (VEGFR1) in murine heart, lung and kidney.

Cell and tissue research Jul, 2016 | Pubmed ID: 26928042

Lipocalin-2 as an Infection-Related Biomarker to Predict Clinical Outcome in Ischemic Stroke.

PloS one , 2016 | Pubmed ID: 27152948

Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.

Proceedings of the National Academy of Sciences of the United States of America 02, 2017 | Pubmed ID: 28196884

Widespread cortical demyelination of both hemispheres can be induced by injection of pro-inflammatory cytokines via an implanted catheter in the cortex of MOG-immunized rats.

Experimental neurology 08, 2017 | Pubmed ID: 28457906

Preclinical toxicological assessment of a novel monoclonal antibody targeting human platelet-derived growth factor CC (PDGF-CC) in PDGF-CChum mice.

PloS one , 2018 | Pubmed ID: 30021009

Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis.

Clinical epigenetics 05, 2019 | Pubmed ID: 31146783

C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation.

The Journal of clinical investigation 02, 2020 | Pubmed ID: 31725411

Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.

Science immunology 10, 2020 | Pubmed ID: 33067381

Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA ().

Frontiers in neurology , 2020 | Pubmed ID: 33304315

Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood-brain barrier.

Scientific reports 12, 2020 | Pubmed ID: 33361796

Anti-CD20 treatment effectively attenuates cortical pathology in a rat model of widespread cortical demyelination.

Journal of neuroinflammation Jun, 2021 | Pubmed ID: 34130726

INSTITUTIONS

Karolinska Institutet

Medical University of Vienna

JOVE ARTICLES

Immunohistochemical Analysis in the Rat Central Nervous System and Peripheral Lymph Node Tissue Sections

Milena Z. Adzemovic^1,2,

Manuel Zeitelhofer^1,3,

Marianne Leisser²,

Ulricke Köck²,

Angela Kury²,

Tomas Olsson¹

¹Department of Clinical Neuroscience, Neuroimmunology Unit, Center for Molecular Medicine, Karolinska Institutet,

²Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna,

³Department of Medical Biochemistry and Biophysics, Vascular Biology Unit, Karolinska Institutet

Neuroscience

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines

Muammer Üçal^*,1,

Michaela Tanja Haindl^*,2,

Milena Z. Adzemovic³,

Manuel Zeitelhofer⁴,

Ute Schaefer¹,

Franz Fazekas²,

Sonja Hochmeister²

¹Research Unit of Experimental Neurotraumatology, Department of Neurosurgery, Medical University Graz,

²Department of Neurology, Medical University Graz,

³Centre for Molecular Medicine, Department of Clinical Neuroscience, Karolinska Institutet,

⁴Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet

Neuroscience

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