Protein Target Prediction and Validation of Small Molecule Compound

2.3K Views

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10:21 min

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February 23rd, 2024

DOI :

10.3791/66564-v

February 23rd, 2024

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Liuling Luo¹, Jinrui Xiong¹, Yancai Tang¹, Xiaorui Chen¹, Hai Zhang¹

¹State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy/School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine

Transcript

Summary

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Protein Target Prediction

Small Molecule Compounds

Molecular Docking

Cellular Thermal Shift Assay

CETSA

Drug Development

Protein ligand Binding

Experimental Validation

Chapters in this video

0:00

Introduction

1:04

Molecular Docking to Investigate the Interaction Between Xanthatin and Keap1 Protein

3:38

Cell Culture and Cellular Thermal Shift Assay (CETSA) Sample Preparation for Western Blotting

6:11

Verification of the Interaction Between Xanthatin and Keap1 Protein Using Western Blotting

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