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蛛网膜下腔出血急性和后遗症的研究兔血分流型号:技术问题

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13.5K Views

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09:00 min

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October 2nd, 2014

DOI :

10.3791/52132-v

October 2nd, 2014

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Lukas Andereggen³^,⁴^,⁵, Volker Neuschmelting¹^,⁶, Michael von Gunten⁷, Hans Rudolf Widmer⁵, Jukka Takala¹, Stephan M. Jakob¹, Javier Fandino¹^,², Serge Marbacher¹^,²

¹Department of Intensive Care Medicine, University and Bern University Hospital (Inselspital), ²Department of Neurosurgery, Kantonsspital Aarau, ³Laboratories for Neuroscience Research in Neurosurgery, Boston Children's Hospital, ⁴Harvard Medical School, Boston Children's Hospital, ⁵Department of Neurosurgery, University and Bern University Hospital (Inselspital), ⁶Department of Neurosurgery, University Hospital Cologne, ⁷Institute of Pathology, Länggasse Bern

摘要

The experimental intracranial pressure-controlled blood shunt subarachnoid hemorrhage (SAH) model in the rabbit combines the standard procedures — subclavian artery cannulation and transcutaneous cisterna magna puncture, which enables close mimicking of human pathophysiological conditions after SAH. We present step-by-step instructions and discuss key surgical points for successful experimental SAH creation.

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此视频中的章节

0:05

Title

1:18

Subclavian Artery Cannulation

3:15

Baseline Digital Subtraction Angiography

3:48

Installation of Intracranial Pressure and Cerebral Blood Flow Monitoring

5:55

Shunt Induction

7:32

Results: Representative Subarachnoid Hemorrhage (SAH) Analyses

8:34

Conclusion

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