Results: c-Fos and Dusp1 Therapeutic Target in Leukemia
9:36
Conclusion
副本
This method can help answer key questions in cancer therapeutics fields, such as identification of key genes involved in oncogene dependence. The main advantage of this technique is that it utilizes the oncogene dependence that is common to many k
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Here, we describe protocols for the genetic and chemical validation of c-Fos and Dusp1 as a drug target in leukemia using in vitro and in vivo genetic and humanized mouse models. This method can be applied to any target for genetic validation and therapeutic development.
