Implanting Electroencephalogram (EEG) and Electrocardiogram (ECG) Electrodes and Attaching Respiratory Monitors
2:45
Video EEG-ECG Recording
3:32
Photic Stimulation
4:59
Oral Medication Administration
5:52
Intravenous Medication Administration
7:08
Analysis of ECG and Video-EEG
8:23
Results: Identification of Seizures and Arrhythmias in Conscious Restrained Rabbits
9:41
Conclusion
副本
Cardiac and respiratory dysfunction contributes to sudden death after a seizure. Therefore, to study this phenomenon, a multi-system approach was applied to a rabbit model. This technique enables simultaneous monitoring and later analysis of the n
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Using simultaneous video-EEG-ECG-oximetry-capnography, we developed a methodology to evaluate the susceptibility of rabbit models to develop provoked arrhythmias and seizures. This novel recording system establishes a platform to test the efficacy and safety of therapeutics and can capture the complex cascade of multi-system events that culminate in sudden death.