Michael Clay

Spectroscopic studies of Pyrococcus furiosus superoxide reductase: implications for active-site structures and the catalytic mechanism.

Heterodisulfide reductase from Methanothermobacter marburgensis contains an active-site [4Fe-4S] cluster that is directly involved in mediating heterodisulfide reduction.

A hyperthermophilic plant-type [2Fe-2S] ferredoxin from Aquifex aeolicus is stabilized by a disulfide bond.

Superoxide reductase: fact or fiction?

Resonance Raman characterization of the mononuclear iron active-site vibrations and putative electron transport pathways in Pyrococcus furiosus superoxide reductase.

Nitric oxide binding at the mononuclear active site of reduced Pyrococcus furiosus superoxide reductase.

Spectroscopic characterization of the [Fe(His)(4)(Cys)] site in 2Fe-superoxide reductase from Desulfovibrio vulgaris.

Synthesis and structure-activity relationships of novel arylpiperazines as potent and selective agonists of the melanocortin subtype-4 receptor.

Spectroscopic investigation of the nickel-containing porphinoid cofactor F(430). Comparison of the free cofactor in the (+)1, (+)2 and (+)3 oxidation states with the cofactor bound to methyl-coenzyme M reductase in the silent, red and ox forms.

Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3.

Synthesis and biological evaluation of an orally active ghrelin agonist that stimulates food consumption and adiposity in rats.

Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.

LY503430: pharmacology, pharmacokinetics, and effects in rodent models of Parkinson's disease.

Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist.

Geometries and electronic structures of cyanide adducts of the non-heme iron active site of superoxide reductases: vibrational and ENDOR studies.

Spectroscopy and electronic structures of mono- and binuclear high-valent non-heme iron-oxo systems.

Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes.

Comparing the electronic properties of the low-spin cyano-ferric [Fe(N4)(Cys)] active sites of superoxide reductase and p450cam using ENDOR spectroscopy and DFT calculations.

Azetidinones as vasopressin V1a antagonists.

Spectroscopic and electronic structure studies of intermediate X in ribonucleotide reductase R2 and two variants: a description of the FeIV-oxo bond in the FeIII-O-FeIV dimer.

Catalytic effectiveness, a measure of enzyme proficiency for industrial applications.

Peroxo-type intermediates in class I ribonucleotide reductase and related binuclear non-heme iron enzymes.

No evidence of human clonally transmissible anogenital cancer.

Microscopic uterine lymphangioleiomyomatosis perivascular epithelioid cell neoplasm: a case report with the earliest manifestation of this enigmatic neoplasm.

Conditional ablation of macrophages disrupts ovarian vasculature.

Clinicopathologic characteristics of HER2 FISH-ambiguous breast cancer at a single institution.

Teaching while learning while practicing: reframing faculty development for the patient-centered medical home.

MAST2 and NOTCH1 translocations in breast carcinoma and associated pre-invasive lesions.

Epidemiology of concussion in sport: a literature review.