Tissue Harvesting and Analysis of Plaque Composition
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Results
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Conclusion
Transkript
The overall goal of this procedure is to induce the formation of atherosclerotic plaques in rabbits by surgically disrupting the endothelium of their left iliac arteries, and feeding them an atherogenic diet. By lone injury in rabbits is often per
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Animal models of atherosclerosis are essential to understand the mechanism and to investigate newer approaches to prevent plaque development or rupture, a leading cause of death in the industrialized world. This protocol uses a combination of balloon injury and cholesterol rich diet to induce atherosclerotic plaques in rabbit iliac artery.