Results: Chronic Immobilization Stress (CIS) Induces Depressive-like Behaviors Well and Releases the Stress Marker Corticosterone
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Conclusion
Transkript
Begin by setting the room to light at 200 lux using a digital lux meter. House the mouse in a separate cage at least a week before testing, and place the mouse in the testing room for at least 30 minutes before the experiment. Gently hold the mous
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This article provides a simplified and standardized protocol for induction of depressive-like behavior in chronically immobilized mice by using a restrainer. In addition, behavior and physiological techniques to verify induction of depression are explained.