Korkut Uygun

Investigation of metabolic objectives in cultured hepatocytes.

A model for normothermic preservation of the rat liver.

Tissue growth modeling in a wavy-walled bioreactor.

Recovery of warm ischemic rat liver grafts by normothermic extracorporeal perfusion.

High-throughput single cell arrays as a novel tool in biopreservation.

Effects of burn injury on markers of hypermetabolism in rats.

Cell delivery: from cell transplantation to organ engineering.

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix.

Optimization-based metabolic control analysis.

In situ metabolic flux analysis to quantify the liver metabolic response to experimental burn injury.

In situ metabolic flux analysis to quantify the liver metabolic response to experimental burn injury.

Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds.

Subnormothermic Machine Perfusion at Both 20°C and 30°C Recovers Ischemic Rat Livers for Successful Transplantation.

A novel 3D liver organoid system for elucidation of hepatic glucose metabolism.

A metabolic index of ischemic injury for perfusion-recovery of cadaveric rat livers.

A fitness index for transplantation of machine-perfused cadaveric rat livers.

Application of whole-organ tissue engineering in hepatology.

A simplified subnormothermic machine perfusion system restores ischemically damaged liver grafts in a rat model of orthotopic liver transplantation.

Supercooling as a viable non-freezing cell preservation method of rat hepatocytes.

Strategies to rescue steatotic livers before transplantation in clinical and experimental studies.

Resuscitation of ischemic donor livers with normothermic machine perfusion: a metabolic flux analysis of treatment in rats.

Determination and extension of the limits to static cold storage using subnormothermic machine perfusion.

Injury to peribiliary glands and vascular plexus before liver transplantation predicts formation of non-anastomotic biliary strictures.

Development of Metabolic Indicators of Burn Injury: Very Low Density Lipoprotein (VLDL) and Acetoacetate Are Highly Correlated to Severity of Burn Injury in Rats.

Supercooling enables long-term transplantation survival following 4 days of liver preservation.

Organomatics and organometrics: Novel platforms for long-term whole-organ culture.

SIMPLE MACHINE PERFUSION SIGNIFICANTLY ENHANCES HEPATOCYTE YIELDS OF ISCHEMIC AND FRESH RAT LIVERS.

Supercooling preservation and transplantation of the rat liver.

Surgical models of Roux-en-Y gastric bypass surgery and sleeve gastrectomy in rats and mice.

Warm Ischemic Injury Is Reflected in the Release of Injury Markers during Cold Preservation of the Human Liver.

Systems engineering the organ preservation process for transplantation.

Sequential cold storage and normothermic perfusion of the ischemic rat liver.

Diluted blood reperfusion as a model for transplantation of ischemic rat livers: alanine aminotransferase is a direct indicator of viability.

Perfusion defatting at subnormothermic temperatures in steatotic rat livers.

Machine perfusion enhances hepatocyte isolation yields from ischemic livers.

Metabolic profiling during ex vivo machine perfusion of the human liver.

Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection.

Peritransplant Energy Changes and Their Correlation to Outcome After Human Liver Transplantation.

Liver ex situ machine perfusion preservation: A review of the methodology and results of large animal studies and clinical trials.

Subzero organ preservation: the dawn of a new ice age?

The promise of organ and tissue preservation to transform medicine.

A highly-occupied, single-cell trapping microarray for determination of cell membrane permeability.

Metabolomic Modularity Analysis (MMA) to Quantify Human Liver Perfusion Dynamics.

Improved Cuff Technique and Intraoperative Detection of Vascular Complications for Hind Limb Transplantation in Mice.

Caspase Inhibition: Optimizing Grafts for Transplantation.

Multi-omic network-based interrogation of rat liver metabolism following gastric bypass surgery featuring SWATH proteomics.

Endothelial Dysfunction in Steatotic Human Donor Livers: A Pilot Study of the Underlying Mechanism During Subnormothermic Machine Perfusion.

Advances in machine perfusion, organ preservation, and cryobiology: potential impact on vascularized composite allotransplantation.

Oxygenated UW Solution Decreases ATP Decay and Improves Survival After Transplantation of DCD Liver Grafts.

Contrast-Enhanced Ultrasound to Quantifyc Perfusion in a Machine-Perfused Pig Liver.

Bulk Droplet Vitrification: An Approach to Improve Large-Scale Hepatocyte Cryopreservation Outcome.

Specific Patterns of Postoperative Temperature Elevations Predict Blood Infection in Pediatric Burn Patients.

Increasing Donor Liver Utilization Through Machine Perfusion.

Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis.

Synthetic hemoglobin-based oxygen carriers are an acceptable alternative for packed red blood cells in normothermic kidney perfusion.

A novel model for ex situ reperfusion of the human liver following subnormothermic machine perfusion.

The efficacy of HBOC-201 in ex situ gradual rewarming kidney perfusion in a rat model.

Exploring donor demographics effects on hepatocyte yield and viability: Results of whole human liver isolation from one center.

Leveraging the zebrafish to model organ transplantation.

Supercooling extends preservation time of human livers.

Effect of Ice Nucleation and Cryoprotectants during High Subzero-Preservation in Endothelialized Microchannels.

Subnormothermic Machine Perfusion of Steatotic Livers Results in Increased Energy Charge at the Cost of Anti-Oxidant Capacity Compared to Normothermic Perfusion.

Pumping new life into old ideas: Preservation and rehabilitation of the liver using ex situ machine perfusion.

Ex vivo perfusion-based engraftment of genetically engineered cell sensors into transplantable organs.

Split-Liver Ex Situ Machine Perfusion: A Novel Technique for Studying Organ Preservation and Therapeutic Interventions.

Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies.

Cell release during perfusion reflects cold ischemic injury in rat livers.

Improvement of steatotic rat liver function with a defatting cocktail during ex situ normothermic machine perfusion is not directly related to liver fat content.

Subzero non-frozen preservation of human livers in the supercooled state.

Tryptophan Metabolism via the Kynurenine Pathway: Implications for Graft Optimization during Machine Perfusion.

Viability testing of discarded livers with normothermic machine perfusion: Alleviating the organ shortage outweighs the cost.

Multiorgan Metabolomics and Lipidomics Provide New Insights Into Fat Infiltration in the Liver, Muscle Wasting, and Liver-Muscle Crosstalk Following Burn Injury.

A portable single-sided magnetic-resonance sensor for the grading of liver steatosis and fibrosis.

Evolving utilization of donation after circulatory death livers in liver transplantation: The day of DCD has come.

Liver donor age affects hepatocyte function through age-dependent changes in decellularized liver matrix.

In Vivo Activity of Genetically Modified Cells Preseeded in Rat Vascularized Composite Allografts.

Thrombolytic Therapy During Normothermic Machine Perfusion of Human Livers Reduces Peribiliary Vascular Plexus Injury.

Twenty-four hour ex-vivo normothermic machine perfusion in rat livers.

Optimization of Ex Vivo Machine Perfusion and Transplantation of Vascularized Composite Allografts.

Non-invasive quantification of the mitochondrial redox state in livers during machine perfusion.

Activation of autophagy during normothermic machine perfusion of discarded livers is associated with improved hepatocellular function.

The effect of blood cells retained in rat livers during static cold storage on viability outcomes during normothermic machine perfusion.

CYP450 drug inducibility in NAFLD via an in vitro hepatic model: Understanding drug-drug interactions in the fatty liver.

Specific patterns of vital sign fluctuations predict infection and enable sepsis diagnosis in pediatric burn patients.

Modeling energy depletion in rat livers using Nash equilibrium metabolic pathway analysis.

Exceeding the Limits of Static Cold Storage in Limb Transplantation Using Subnormothermic Machine Perfusion.

Partial freezing of rat livers extends preservation time by 5-fold.

A Novel Digital Algorithm for Identifying Liver Steatosis Using Smartphone-Captured Images.

Pan-caspase inhibition during normothermic machine perfusion of discarded livers mitigates innate immune responses.

Subnormothermic Ex Vivo Porcine Kidney Perfusion Improves Energy Metabolism: Analysis Using P Magnetic Resonance Spectroscopic Imaging.

Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study.

Development of a rat forelimb vascularized composite allograft (VCA) perfusion protocol.

Continuous versus Pulsatile Flow in 24-Hour Vascularized Composite Allograft Machine Perfusion in Swine: A Pilot Study.

The role of antifreeze glycoprotein (AFGP) and polyvinyl alcohol/polyglycerol (X/Z-1000) as ice modulators during partial freezing of rat livers.

Gluteal Propeller Perforator Flaps: A Paradigm Shift in Abdominoperineal Amputation Reconstruction.

Response Regarding: Continuous Versus Pulsatile Flow in 24-h Vascularized Composite Allograft Machine Perfusion in Swine: A Pilot Study.

Towards Optimizing Sub-Normothermic Machine Perfusion in Fasciocutaneous Flaps: A Large Animal Study.

The Autonomization Principle in Vascularized Flaps: An Alternative Strategy for Composite Tissue Scaffold In Vivo Revascularization.

VCA supercooling in a swine partial hindlimb model.

Continuous oxygen monitoring to enhance ex-vivo organ machine perfusion and reconstructive surgery.

Sub-zero non-freezing of vascularized composite allografts in a rodent partial hindlimb model.

Supercooling preservation of vascularized composite allografts through CPA optimization, thermal tracking, and stepwise loading techniques.

Optimized partial freezing protocol enables 10-day storage of rat livers.

Enhanced VCA Storage: A Pilot Study Demonstrating Supercooling in Orthotopic Rodent Hindlimb Transplantation.