Department of Ophthalmology and Visual Sciences,
Omics Laboratory,
Ophthalmology and Visual Sciences,
Department of Ophthalmology and Visual Sciences, Omics Laboratory
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Microarray analysis of corneal fibroblast gene expression after interleukin-1 treatment.
Investigative ophthalmology & visual science Jul, 2002 | Pubmed ID: 12091409
Tissue-specific gene expression of head and neck squamous cell carcinoma in vivo by complementary DNA microarray analysis.
Archives of otolaryngology--head & neck surgery Jul, 2003 | Pubmed ID: 12874079
Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women.
American journal of epidemiology May, 2008 | Pubmed ID: 18359774
A head-tilt test for hypopyon after intravitreal triamcinolone.
Retina (Philadelphia, Pa.) Apr, 2009 | Pubmed ID: 19092731
Management of sympathetic ophthalmia with the fluocinolone acetonide implant.
Ophthalmology Mar, 2009 | Pubmed ID: 19147232
A new macular dystrophy with anomalous vascular development, pigment spots, cystic spaces, and neovascularization.
Archives of ophthalmology Nov, 2009 | Pubmed ID: 19901210
Erythropoetin receptor expression in the human diabetic retina.
BMC research notes , 2009 | Pubmed ID: 19930719
Effects of vitrectomy on age-related macular degeneration.
Ophthalmology Jul, 2010 | Pubmed ID: 20176401
Automated early detection of diabetic retinopathy.
Ophthalmology Jun, 2010 | Pubmed ID: 20399502
T-cell infiltration in autosomal dominant neovascular inflammatory vitreoretinopathy.
Molecular vision , 2010 | Pubmed ID: 20596252
Patients with an acute zonal occult outer retinopathy-like illness rapidly improve with valacyclovir treatment.
American journal of ophthalmology Oct, 2010 | Pubmed ID: 20691421
Collagen XVIII mutation in Knobloch syndrome with acute lymphoblastic leukemia.
American journal of medical genetics. Part A Nov, 2010 | Pubmed ID: 20799329
Intravitreal bevacizumab during pregnancy.
Retina (Philadelphia, Pa.) Oct, 2010 | Pubmed ID: 20924262
Bilateral intravitreal injection of antivascular endothelial growth factor therapy.
Retina (Philadelphia, Pa.) Jan, 2011 | Pubmed ID: 21187731
Intraoperative choroidal detachment during 23-gauge vitrectomy.
Retina (Philadelphia, Pa.) May, 2011 | Pubmed ID: 21273944
Mutations in prickle orthologs cause seizures in flies, mice, and humans.
American journal of human genetics Feb, 2011 | Pubmed ID: 21276947
Seroreactivity against aqueous-soluble and detergent-soluble retinal proteins in posterior uveitis.
Archives of ophthalmology Apr, 2011 | Pubmed ID: 21482867
Sutureless triplanar sclerotomy for 23-gauge vitrectomy.
Archives of ophthalmology May, 2011 | Pubmed ID: 21555611
Intravitreal bevacizumab for treatment of proliferative and nonproliferative type 2 idiopathic macular telangiectasia.
Retina (Philadelphia, Pa.) Oct, 2011 | Pubmed ID: 21610563
Uveitis following intravitreal bevacizumab: a non-infectious cluster.
Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye Jul-Aug, 2011 | Pubmed ID: 21800802
Automated discovery and quantification of image-based complex phenotypes: a twin study of drusen phenotypes in age-related macular degeneration.
Investigative ophthalmology & visual science , 2011 | Pubmed ID: 22039249
Correspondence.
Retina (Philadelphia, Pa.) Feb, 2012 | Pubmed ID: 22222759
Infrared Imaging and Optical Coherence Tomography Reveal Early-Stage Astrocytic Hamartomas Not Detectable by Fundoscopy.
American journal of ophthalmology Feb, 2012 | Pubmed ID: 22310082
Unexpected mutations after CRISPR-Cas9 editing in vivo.
Nature methods May, 2017 | Pubmed ID: 28557981
CRISPR-Cas Genome Surgery in Ophthalmology.
Translational vision science & technology May, 2017 | Pubmed ID: 28573077
Limbal Trocar-Cannulas for Complex Vitrectomy Surgery.
Retina (Philadelphia, Pa.) Jul, 2017 | Pubmed ID: 28737532
Retinal and choroidal angiogenesis: a review of new targets.
International journal of retina and vitreous , 2017 | Pubmed ID: 28835854
Retrospective Analysis of Structural Disease Progression in Retinitis Pigmentosa Utilizing Multimodal Imaging.
Scientific reports Sep, 2017 | Pubmed ID: 28871101
Electroretinography Reveals Difference in Cone Function between Syndromic and Nonsyndromic USH2A Patients.
Scientific reports Sep, 2017 | Pubmed ID: 28894305
CRISPR-mediated Ophthalmic Genome Surgery.
Current ophthalmology reports Sep, 2017 | Pubmed ID: 28966884
Signal Normalization Reduces Image Appearance Disparity Among Multiple Optical Coherence Tomography Devices.
Translational vision science & technology Feb, 2017 | Pubmed ID: 28275528
Calpain-5 gene expression in the mouse eye and brain.
BMC research notes Nov, 2017 | Pubmed ID: 29157313
Gene Therapy Restores Mfrp and Corrects Axial Eye Length.
Scientific reports 11, 2017 | Pubmed ID: 29170418
CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa: A Brief Methodology.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29188514
Personalized Proteomics in Proliferative Vitreoretinopathy Implicate Hematopoietic Cell Recruitment and mTOR as a Therapeutic Target.
American journal of ophthalmology 02, 2018 | Pubmed ID: 29246578
Genome Surgery and Gene Therapy in Retinal Disorders.
The Yale journal of biology and medicine 12, 2017 | Pubmed ID: 29259518
Therapeutic drug repositioning using personalized proteomics of liquid biopsies.
JCI insight Dec, 2017 | Pubmed ID: 29263305
Autologous stem cell therapy for inherited and acquired retinal disease.
Regenerative medicine Jan, 2018 | Pubmed ID: 29360008
Bevacizumab Injection in Patients with Neovascular Age-Related Macular Degeneration Increases Angiogenic Biomarkers.
Ophthalmology. Retina Jan, 2018 | Pubmed ID: 29376143
Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic- and oxidative stress-related diseases.
PloS one , 2018 | Pubmed ID: 29466423
A novel de novo mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay.
Cold Spring Harbor molecular case studies Jun, 2018 | Pubmed ID: 29472286
Caring for Hereditary Childhood Retinal Blindness.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) May-Jun, 2018 | Pubmed ID: 29536675
Acute vitreoretinal trauma and inflammation after traumatic brain injury in mice.
Annals of clinical and translational neurology Mar, 2018 | Pubmed ID: 29560370
HTRA1, an age-related macular degeneration protease, processes extracellular matrix proteins EFEMP1 and TSP1.
Aging cell Aug, 2018 | Pubmed ID: 29730901
CRISPR GENOME SURGERY IN THE RETINA IN LIGHT OF OFF-TARGETING.
Retina (Philadelphia, Pa.) Aug, 2018 | Pubmed ID: 29746416
Deferoxamine-induced electronegative ERG responses.
Documenta ophthalmologica. Advances in ophthalmology 08, 2018 | Pubmed ID: 29770904
Gene therapy and genome surgery in the retina.
The Journal of clinical investigation Jun, 2018 | Pubmed ID: 29856367
Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases.
Frontiers in cell and developmental biology , 2018 | Pubmed ID: 29876348
Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface.
Free radical biology & medicine 08, 2018 | Pubmed ID: 29940351
Rates of Bone Spicule Pigment Appearance in Patients With Retinitis Pigmentosa Sine Pigmento.
American journal of ophthalmology Nov, 2018 | Pubmed ID: 30081015
Missense mutation in SLIT2 associated with congenital myopia, anisometropia, connective tissue abnormalities, and obesity.
Orphanet journal of rare diseases Aug, 2018 | Pubmed ID: 30111362
Quantitative progression of retinitis pigmentosa by optical coherence tomography angiography.
Scientific reports 09, 2018 | Pubmed ID: 30177829
Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease.
Translational vision science & technology Sep, 2018 | Pubmed ID: 30271679
PROGRESSION OF SCOTOPIC SINGLE-FLASH ELECTRORETINOGRAPHY IN THE STAGES OF CAPN5 VITREORETINOPATHY.
Retinal cases & brief reports Jul, 2021 | Pubmed ID: 30300311
ProSave: an application for restoring quantitative data to manipulated subsets of protein lists.
Source code for biology and medicine , 2018 | Pubmed ID: 30459825
Review of Ocular Manifestations of Joubert Syndrome.
Genes Dec, 2018 | Pubmed ID: 30518138
SCAPER-associated nonsyndromic autosomal recessive retinitis pigmentosa.
American journal of medical genetics. Part A Feb, 2019 | Pubmed ID: 30561111
In Vivo Expression of Mutant Calpains in the Eye Using Lentivirus.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30617808
Viral Delivery Systems for CRISPR.
Viruses Jan, 2019 | Pubmed ID: 30621179
Fundus autofluorescence and ellipsoid zone (EZ) line width can be an outcome measurement in RHO-associated autosomal dominant retinitis pigmentosa.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Apr, 2019 | Pubmed ID: 30635721
VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site.
Investigative ophthalmology & visual science 01, 2019 | Pubmed ID: 30657523
Optical Coherence Tomography Angiography of RPGR-Associated Retinitis Pigmentosa Suggests Foveal Avascular Zone is a Biomarker for Vision Loss.
Ophthalmic surgery, lasers & imaging retina Feb, 2019 | Pubmed ID: 30768229
Traumatic chorioretinitis sclopetaria: Risk factors, management, and prognosis.
American journal of ophthalmology case reports Jun, 2019 | Pubmed ID: 30834355
Mechanisms of neurodegeneration in a preclinical autosomal dominant retinitis pigmentosa knock-in model with a Rho mutation.
Cellular and molecular life sciences : CMLS Sep, 2019 | Pubmed ID: 30976840
Early Onset Neovascular Inflammatory Vitreoretinopathy Due to a Mutation: Report of a Case.
Ocular immunology and inflammation , 2019 | Pubmed ID: 30986125
Therapeutic Window for Phosphodiesterase 6-Related Retinitis Pigmentosa.
JAMA ophthalmology Jun, 2019 | Pubmed ID: 30998807
Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse.
eLife 05, 2019 | Pubmed ID: 31090540
Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy.
Scientific reports May, 2019 | Pubmed ID: 31110225
Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2019 | Pubmed ID: 31138708
Bilateral Endophthalmitis after Immediately Sequential Bilateral Cataract Surgery.
Ophthalmology. Retina Jul, 2019 | Pubmed ID: 31153851
In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth.
Genetics research Jun, 2019 | Pubmed ID: 31190668
CRISPR Base Editing in Induced Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 31250381
Comparison of structural progression between ciliopathy and non-ciliopathy associated with autosomal recessive retinitis pigmentosa.
Orphanet journal of rare diseases Aug, 2019 | Pubmed ID: 31370859
Opposing T cell responses in experimental autoimmune encephalomyelitis.
Nature Aug, 2019 | Pubmed ID: 31391585
CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials.
Human mutation Dec, 2019 | Pubmed ID: 31403230
Hypoxic drive caused Type 3 neovascularization in a preclinical model of exudative age-related macular degeneration.
Human molecular genetics Sep, 2019 | Pubmed ID: 31518400
Novel REEP6 gene mutation associated with autosomal recessive retinitis pigmentosa.
Documenta ophthalmologica. Advances in ophthalmology Feb, 2020 | Pubmed ID: 31538292
Compound heterozygous novel frameshift variants in the gene result in Leber congenital amaurosis.
Cold Spring Harbor molecular case studies Dec, 2019 | Pubmed ID: 31836589
Novel mutations in the 3-box motif of the BACK domain of KLHL7 associated with nonsyndromic autosomal dominant retinitis pigmentosa.
Orphanet journal of rare diseases Dec, 2019 | Pubmed ID: 31856884
Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants.
Cell reports Jan, 2020 | Pubmed ID: 31968260
Fundoscopy-directed genetic testing to re-evaluate negative whole exome sequencing results.
Orphanet journal of rare diseases Jan, 2020 | Pubmed ID: 32000842
Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration.
EBioMedicine Feb, 2020 | Pubmed ID: 32028070
Modulation of Post-Traumatic Immune Response Using the IL-1 Receptor Antagonist Anakinra for Improved Visual Outcomes.
Journal of neurotrauma Jun, 2020 | Pubmed ID: 32056479
Phenotypic variance in Calpain-5 retinal degeneration.
American journal of ophthalmology case reports Jun, 2020 | Pubmed ID: 32274441
Proteomic analysis of intermediate uveitis suggests myeloid cell recruitment and implicates IL-23 as a therapeutic target.
American journal of ophthalmology case reports Jun, 2020 | Pubmed ID: 32274442
Reply.
Retina (Philadelphia, Pa.) Aug, 2020 | Pubmed ID: 32343099
Optical Gap Biomarker in Cone-Dominant Retinal Dystrophy.
American journal of ophthalmology Oct, 2020 | Pubmed ID: 32445700
Quantitative Autofluorescence Following Gene Therapy With Voretigene Neparvovec.
JAMA ophthalmology Aug, 2020 | Pubmed ID: 32556084
Sex Differences in the Repair of Retinal Detachments in the United States.
American journal of ophthalmology Nov, 2020 | Pubmed ID: 32640255
Whole-Exome Sequencing of Patients With Posterior Segment Uveitis.
American journal of ophthalmology Jan, 2021 | Pubmed ID: 32707200
Intravitreal methotrexate and fluocinolone acetonide implantation for Vogt-Koyanagi-Harada uveitis.
American journal of ophthalmology case reports Sep, 2020 | Pubmed ID: 32793845
Sex Does Not Influence Visual Outcomes After Blast-Mediated Traumatic Brain Injury but IL-1 Pathway Mutations Confer Partial Rescue.
Investigative ophthalmology & visual science Oct, 2020 | Pubmed ID: 33030508
Retinal Manifestations of Mitochondrial Oxidative Phosphorylation Disorders.
Investigative ophthalmology & visual science Oct, 2020 | Pubmed ID: 33049060
Molecular Surgery: Proteomics of a Rare Genetic Disease Gives Insight into Common Causes of Blindness.
iScience Nov, 2020 | Pubmed ID: 33134897
Liquid biopsy proteomics of uveal melanoma reveals biomarkers associated with metastatic risk.
Molecular cancer Feb, 2021 | Pubmed ID: 33627107
Peptidomimetics Therapeutics for Retinal Disease.
Biomolecules Feb, 2021 | Pubmed ID: 33668179
Telegenetics for inherited retinal diseases in the COVID-19 environment.
International journal of retina and vitreous Mar, 2021 | Pubmed ID: 33781332
Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.
The Journal of clinical investigation May, 2021 | Pubmed ID: 33844653
Genetics of Uveitis.
Ocular immunology and inflammation Feb, 2021 | Pubmed ID: 33950774
Molecular Characterization of a Rare Case of Bilateral Vitreoretinal T Cell Lymphoma through Vitreous Liquid Biopsy.
International journal of molecular sciences Jun, 2021 | Pubmed ID: 34198843
The Present and Future of Mitochondrial-Based Therapeutics for Eye Disease.
Translational vision science & technology Jul, 2021 | Pubmed ID: 34232272
Proteomics in uveal melanoma.
Current opinion in ophthalmology May, 2022 | Pubmed ID: 35102096
An intravitreal implant injection method for sustained drug delivery into mouse eyes.
Cell reports methods Dec, 2021 | Pubmed ID: 35128514
A protocol to inject ocular drug implants into mouse eyes.
STAR protocols Mar, 2022 | Pubmed ID: 35141566
Investigation of Cas9 antibodies in the human eye.
Nature communications Feb, 2022 | Pubmed ID: 35217666
Surgical management of acanthamoeba chorioretinitis.
American journal of ophthalmology case reports Mar, 2022 | Pubmed ID: 35243145
New COL6A6 Variant Causes Autosomal Dominant Retinitis Pigmentosa in a Four-Generation Family.
Investigative ophthalmology & visual science Mar, 2022 | Pubmed ID: 35333290
Expanding the phenotype of TTLL5-associated retinal dystrophy: a case series.
Orphanet journal of rare diseases Apr, 2022 | Pubmed ID: 35365235
Retinal artery and vein occlusion in calciphylaxis.
American journal of ophthalmology case reports Jun, 2022 | Pubmed ID: 35372715
Author Correction: Investigation of Cas9 antibodies in the human eye.
Nature communications Apr, 2022 | Pubmed ID: 35414059
Multimodal imaging reveals retinoschisis masquerading as retinal detachment in patients with choroideremia.
American journal of ophthalmology case reports Jun, 2022 | Pubmed ID: 35496760
Proteomic analysis of autoimmune retinopathy implicates NrCAM as a potential biomarker.
Ophthalmology science Jun, 2022 | Pubmed ID: 35529077
Calpains as mechanistic drivers and therapeutic targets for ocular disease.
Trends in molecular medicine Aug, 2022 | Pubmed ID: 35641420
Bacillary Layer Detachment after Photodynamic Therapy.
Ophthalmology. Retina Jun, 2022 | Pubmed ID: 35680235
Predicting Systemic Health Features from Retinal Fundus Images Using Transfer-Learning-Based Artificial Intelligence Models.
Diagnostics (Basel, Switzerland) Jul, 2022 | Pubmed ID: 35885619
REPRODUCTIVE OPHTHALMOLOGY: The Intersection of Inherited Eye Diseases and Reproductive Technologies.
Retina (Philadelphia, Pa.) Nov, 2022 | Pubmed ID: 35963004
Clinical characteristics of high myopia in female carriers of pathogenic mutations: a case series and review of the literature.
Ophthalmic genetics Jun, 2023 | Pubmed ID: 36017691
Protocol to quantify enzymatic effects on vitreous liquefaction in porcine eyes using a transwell-plate system.
STAR protocols Dec, 2022 | Pubmed ID: 36208453
Chorioretinal atrophy following voretigene neparvovec despite the presence of fundus autofluorescence.
Molecular genetics & genomic medicine Nov, 2022 | Pubmed ID: 36225124
Conjunctival Swabs Reveal Higher Detection Rate Compared to Schirmer Strips for SARS-CoV-2 RNA Detection in Tears of Hospitalized COVID-19 Patients.
Journal of clinical medicine Nov, 2022 | Pubmed ID: 36498504
Intravitreal Fluocinolone Acetonide (Retisert) Implantation Using a Keratome Blade.
Journal of vitreoretinal diseases , 2021 | Pubmed ID: 37009587
Cilia-associated wound repair mediated by IFT88 in retinal pigment epithelium.
Scientific reports May, 2023 | Pubmed ID: 37211572
Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.
Nature methods Jul, 2023 | Pubmed ID: 37291262
AI-Human Hybrid Workflow Enhances Teleophthalmology for the Detection of Diabetic Retinopathy.
Ophthalmology science Dec, 2023 | Pubmed ID: 37449051
Thiago Cabral*,1,2,7,8,
Marcus A. Toral*,3,4,
Gabriel Velez3,4,
James E. DiCarlo1,2,
Anuradha M. Gore3,
MaryAnn Mahajan3,
Stephen H. Tsang1,2,
Alexander G. Bassuk5,6,
Vinit B. Mahajan3,9
1Barbara & Donald Jonas Stem Cell Laboratory, and Bernard & Shirlee Brown Glaucoma Laboratory, Department of Pathology & Cell Biology, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University,
2Edward S. Harkness Eye Institute, New York-Presbyterian Hospital,
3Omics Laboratory, Byers Eye Institute, Department of Ophthalmology, Stanford University,
4Medical Scientist Training Program, University of Iowa,
5Department of Pediatrics, University of Iowa,
6Department of Neurology, University of Iowa,
7Department of Ophthalmology, Federal University of Sao Paulo (UNIFESP),
8Department of Ophthalmology, Federal University of EspÍrito Santo (UFES),
9, Palo Alto Veterans Administration, Palo Alto, CA
Jie Zhang1,2,
Fang Fang1,3,
Liang Li1,
Haoliang Huang1,
Hannah C. Webber1,
Yang Sun1,4,
Vinit B. Mahajan1,4,
Yang Hu1
1Department of Ophthalmology, Stanford University School of Medicine,
2Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,
3Department of Ophthalmology, Second Xiangya Hospital of Central South University,
4Department of Ophthalmology, Veterans Affairs Palo Alto Health Care
Julian Wolf1,2,
Teja Chemudupati1,2,
Aarushi Kumar1,2,
Ditte K. Rasmussen1,2,
Karen M. Wai2,
Robert T. Chang2,
Artis A. Montague2,
Peter H. Tang3,4,
Alexander G. Bassuk5,6,7,
Antoine Dufour8,9,
Prithvi Mruthrunjaya2,
Vinit B. Mahajan1,2,10
1Molecular Surgery Laboratory, Stanford University,
2Department of Ophthalmology, Byers Eye Institute, Stanford University,
3Department of Ophthalmology and Visual Neurosciences, University of Minnesota,
4, Retina Consultants of Minnesota,
5Department of Pediatrics, University of Iowa,
6Department of Neurology, University of Iowa,
7The Iowa Neuroscience Institute (INI), University of Iowa,
8Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary,
9Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary,
10, Veterans Affairs Palo Alto Health Care System
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